The Doris Duke Foundation makes timely strategic investments in support of ideas that advance our mission. We invest in both research and efforts aimed at influencing the culture, practice and policy of clinical research. When appropriate, the foundation issues a limited or open request for applications (RFA). Applications received in response to an RFA typically undergo rigorous internal review as well as external peer review by independent experts. While these grants often fund work conducted by individuals, the direct grant recipient is the associated institution.